The Semaglutide Report

WEGOVY doses

The injection starts at 0.25 mg once a week and steps up every four weeks through 0.5, 1 and 1.7 mg. From week 17 you are on a maintenance dose, and which one that is depends on what the prescription was written for.1

On this page

The injection ladder

The label gives one starting dosage and one escalation table for every approved use of the injection, in adults and in patients aged 12 and older. It is the same climb whatever the prescription is for.1

The WEGOVY injection escalation, once weekly.
StageWeeksDosage
Starting dosage1 through 40.25 mg
Escalation5 through 80.5 mg
Escalation9 through 121 mg
Escalation13 through 161.7 mg
Maintenance17 and onwardDepends on the approved use (below)

WEGOVY prescribing information, Table 1, section 2.2 (label revised 6/2026), read September 2026. It is listed in full under Sources.

Sixteen weeks is nearly four months, and the reason for taking that long is printed beside the table: the escalation exists to reduce the risk of gastrointestinal adverse reactions. How often those turned up, and against what placebo rate, is on the WEGOVY side effects page.1

Maintenance depends on what it was prescribed for

This is the part a dose chart usually flattens. WEGOVY has four approved uses and the label writes a maintenance dosage for each one separately.

The maintenance dosage the label names for each approved use of the injection.
Approved useMaintenance dosage
Cardiovascular risk reduction in adults2.4 mg (recommended) or 1.7 mg once weekly
Weight reduction in adults1.7 mg or 2.4 mg (recommended), and it may be increased to a maximum of 7.2 mg once weekly
Weight reduction from age 122.4 mg (recommended) or 1.7 mg once weekly
Noncirrhotic MASH with F2 to F3 fibrosis in adults2.4 mg once weekly, decreased to 1.7 mg if 2.4 mg is not tolerated

WEGOVY prescribing information, section 2.2, under “Recommended Maintenance Dosage of WEGOVY Injection for All Approved Indications” (label revised 6/2026), read September 2026.

The 7.2 mg row has conditions on it that the number alone does not carry. The label allows it only for weight reduction in adults, only after a patient has tolerated 2.4 mg for at least four weeks, and only where additional weight reduction is clinically indicated. It is not a fifth rung everyone climbs.1

On the MASH row the label adds something the others do not have: if the dosage is decreased to 1.7 mg because 2.4 mg was not tolerated, it says to consider re-escalation to 2.4 mg. Whether a person can settle at 1.7 mg instead is the subject of the page on staying at a low dose, which reports what 1.7 mg measured against 2.4 mg in the label’s own trial.1

If a step is too much

The label writes one instruction for this, and it is worth knowing before the week it applies:

If patients do not tolerate a dose during dosage escalation, consider delaying dosage escalation for 4 weeks.

WEGOVY prescribing information, section 2.2. 1

Delaying is not the same as stopping, and it is not the same as dropping back. Four more weeks at the dose you are already on is the label’s own move, and it is the prescriber’s to make. Missing doses is a different situation with different instructions, and the missed-dose page quotes all three products’ wording in full. Our SELECT trial explanation also shows why the prescribed indication and studied population belong beside a dose comparison.

The tablets run on a different clock

WEGOVY tablets are taken by mouth once a day, and their ladder is measured in days rather than weeks. Four steps, 30 days each, and a maintenance dosage well above the number people expect after reading the injection column.1

The WEGOVY tablet escalation, once daily.
StageDaysDosage
Starting dosage1 through 301.5 mg
Escalation31 through 604 mg
Escalation61 through 909 mg
Maintenance91 and onward25 mg

WEGOVY prescribing information, Table 2, section 2.3 (label revised 6/2026), read September 2026.

What each tablet strength costs is on the WEGOVY pill page, and what the pen costs is on the WEGOVY price page.

Questions

What are the WEGOVY doses in order?

For the injection: 0.25 mg in weeks 1 to 4, 0.5 mg in weeks 5 to 8, 1 mg in weeks 9 to 12, 1.7 mg in weeks 13 to 16, then a maintenance dosage from week 17. For the tablets: 1.5 mg for days 1 to 30, 4 mg for days 31 to 60, 9 mg for days 61 to 90, then 25 mg from day 91.

Is 2.4 mg the highest WEGOVY dose?

Not quite. For weight reduction in adults the label allows an increase to a maximum of 7.2 mg once weekly, after a patient has tolerated 2.4 mg for at least four weeks and where additional weight reduction is clinically indicated. For the other three approved uses, 2.4 mg is the top of the ladder.

How long before I reach the maintenance dose?

Sixteen weeks on the label’s schedule, with the maintenance dosage starting in week 17. A delayed step adds four weeks to that, and the label says to consider delaying escalation by four weeks when a patient does not tolerate a dose.

  • Dosing

    Staying on a low dose of WEGOVY

    What the label calls a maintenance dose, when it says to move up, and what 1.7 mg looked like in the trial.

  • Side effects

    WEGOVY side effects

    What WEGOVY's own label reports, at what rate, against placebo, and how many people stopped.

  • Dosing

    If you missed a dose

    The approved labels give different instructions. All of them, quoted in full.

  • Working it out

    WEGOVY price

    The manufacturer's published pen prices with the date read, and what the $25 and $50 routes require.

Sources

  1. WEGOVY- semaglutide injection, solution; WEGOVY- semaglutide tablet

    DailyMed, U.S. National Library of Medicine. Updated June 18, 2026 — label Revised: 6/2026.

A reference, not medical advice, and not a substitute for your prescriber or pharmacist. If you think you are having a medical emergency, call your local emergency number.